DeSouza-Vieira T, Chan FK. Bacterial pathogenesis: Pathogenic bacteria attack RHIM. Nat Microbiol. 2017 Mar 28;2:17042.
DOI: 10.1038/nmicrobiol.2017.42
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Attaching and effacing enteropathogenic Escherichia coli causes gastrointestinal inflammation and diarrhoea. In this issue of Nature Microbiology, Pearson and colleagues find that this pathology involves bacterial cleavage of a class of host cell death signal adaptors that encode a unique protein interaction motif called the RHIM.